TT virus sequence heterogeneity in vivo: evidence for co-infection with multiple genetic types.
نویسندگان
چکیده
منابع مشابه
TT virus sequence heterogeneity in vivo: evidence for co-infection with multiple genetic types.
TT virus (TTV) is a newly described DNA virus of humans that exhibits an unusually high degree of genetic heterogeneity. We have performed extensive analysis of the TTV populations present in samples, taken over a period of 2 to 6 years, from three individuals with persistent TTV infection. TTV DNA titres estimated for sequential samples were found to be quite stable over the entire study perio...
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TT virus (TTV) is a recently discovered infectious agent originally obtained from transfusion-related hepatitis. However, the causative link between the TTV infection and liver disease remains uncertain. Recent studies demonstrated that genome sequences of different TTV strains are significantly divergent. To assess genetic heterogeneity of the TTV genome in more detail, a sequence analysis of ...
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Although results of IFN alpha therapy in chronic hepatitis C (C-CH) patients co-infected with TT virus (TTV) have been reported, no results of IFN beta therapy or IFN beta and alpha combination therapy have been reported. In this study, we retrospectively investigated whether co-infection with TTV affects the results of IFN therapy by using stored sera from 60 C-CH patients co-infected with TTV...
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TT virus (TTV) is not only an infectious agent of worldwide distribution but has also been demonstrated in various non-human primates in addition to humans. In the present study, we subjected the sera of 67 gibbons to PCR and nucleotide sequencing, with subsequent phylogenetic analysis to determine the nature of the relationship between TTV found in humans and non-human primates. We discovered ...
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ژورنال
عنوان ژورنال: Journal of General Virology
سال: 1999
ISSN: 0022-1317,1465-2099
DOI: 10.1099/0022-1317-80-7-1759